BSN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BSN protein abundance is significantly associated with the RNA expression of many other genes, with 4,982 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BSN-associated genes across cancer lineages are DCAF11, SYP, and GDAP1. Each is linked with BSN in more than 1 cancer types. Because this analysis shows association rather than direction, both BSN-to-partner and partner-to-BSN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BSN versus DCAF11 in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSN→partner) and Y-score (partner→BSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADCAF11 →+0.744+1.563.004.00432
BRCASYP →+3.813+3.001<.001.00132
BRCAGDAP1 →+2.456+2.816.008.00332
BRCARAB3A →+1.376+2.213<.001.00232
BRCACOBL →+1.398+2.179.003.00232
BRCARUNDC3A →+2.952+2.080.004.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,982 associations by consensus.

BSN vs DCAF11 — BRCA

Per-sample scatter of BSN vs DCAF11 in BRCA (Pearson r = 0.40).

Explore this scatter interactively →

Exploration