BSG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BSG protein abundance is significantly associated with the RNA expression of many other genes, with 14,851 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BSG-associated genes across cancer lineages are SLC16A1, ERO1A, and SELP. Each is linked with BSG in more than 7 cancer types. Because this analysis shows association rather than direction, both BSG-to-partner and partner-to-BSG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BSG versus SLC16A1 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSG→partner) and Y-score (partner→BSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASLC16A1 →+1.166+0.590<.001<.00138
HNSCERO1A →+0.826+0.368<.001<.00137
LSCCSELP →-1.157-0.322<.001<.00136
OVCADPS2 →-0.725-0.248.009.00136
LSCCSLC2A1 →+1.072+0.284<.001<.00136
CCRCCTEK →-1.079-0.279<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,851 associations by consensus.

BSG vs SLC16A1 — BRCA

Per-sample scatter of BSG vs SLC16A1 in BRCA (Pearson r = 0.70).

Explore this scatter interactively →

Exploration