BSG

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BSG mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BSG-associated genes across cancer lineages are lymphatic Endothelial cells, CD8+ T-cells, and CD8+ naive T-cells. Each is linked with BSG in more than 1 cancer types. Because this analysis shows association rather than direction, both BSG-to-partner and partner-to-BSG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by BSG-low versus BSG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSG→partner) and Y-score (partner→BSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEClymphatic Endothelial cells →-0.020-3.138.037.01932
HNSCCD8+ T-cells →+0.022+4.015.033.01831
UCECCD8+ naive T-cells →+0.027+3.202.014.00931
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

lymphatic Endothelial cells by BSG expression — UCEC

Box plot of lymphatic Endothelial cells in BSG-low vs BSG-high samples in UCEC.

Explore this box plot interactively →

Exploration