BRWD1-AS2

Across TCGA pan-cancer cohorts, BRWD1-AS2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated BRWD1-AS2 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher BRWD1-AS2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BRWD1-AS2 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRP show a favorable association.

OV, KIRP, and READ are the cancer types where BRWD1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	II,III,IV	0.600	0.469	.002	74	view →
KIRP	DFS	Median	III,IV	0.914	0.138	<.001	42	view →
READ	DFS	Quartile	All	0.924	0.697	.001	36	view →
LUSC	DFS	Tertile	II,III,IV	0.817	0.640	.002	36	view →
UCS	DFS	Tertile	II,III,IV	0.512	0.115	.005	28	view →
PAAD	OS	Tertile	All	0.501	0.223	.007	26	view →
KIRC	DFS	Quartile	II,III,IV	0.722	0.908	.006	20	view →
ACC	OS	Quartile	II,III,IV	0.317	0.859	.012	15	view →
GBM	OS	Quartile	All	0.302	0.456	.009	12	view →
LGG	DFS	Tertile	All	0.563	0.360	.010	10	view →
HNSC	OS	Quartile	IV	0.565	0.329	.015	10	view →
CHOL	OS	Quartile	All	1.000	0.134	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

BRWD1-AS2–OV (DFS)

Open the OV breakdown →