BRMS1L

Across TCGA cell cohorts, BRMS1L mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BRMS1L-associated genes across cancer lineages are TAAR8, IQCF3, and KRTAP19-3. Each is linked with BRMS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both BRMS1L-to-partner and partner-to-BRMS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by BRMS1L-low versus BRMS1L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRMS1L→partner) and Y-score (partner→BRMS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.049	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	1
CNS	PRR23A →	+0.031	+4.981	<.001	.008	3	1
CNS	KRTAP10-3 →	+0.052	+5.754	<.001	.002	3	1
LARGE_INTESTINE	ECE2 →	+0.319	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

TAAR8 by BRMS1L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →