BRIX1P1

Across TCGA patient cohorts, BRIX1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRIX1P1-associated GO terms across cancer lineages are Microtubule-based transport, Chromosome localization, and Spindle assembly. Each is linked with BRIX1P1 in more than 13 cancer types. Because this analysis shows association rather than direction, both BRIX1P1-to-partner and partner-to-BRIX1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by BRIX1P1-low versus BRIX1P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRIX1P1→partner) and Y-score (partner→BRIX1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microtubule-based transport →	+0.052	+0.169	<.001	<.001	3	14
ESCA	Chromosome localization →	+0.081	+0.192	.001	<.001	3	13
LAML	Spindle assembly →	+0.046	+0.135	<.001	<.001	3	13
ESCA	Regulation of DNA recombination →	+0.049	+0.128	.001	<.001	3	13
ESCA	Positive regulation of protein ubiquitination →	+0.052	+0.151	.001	<.001	3	13
ESCA	Protein-containing complex localization →	+0.052	+0.166	.002	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,230 associations by consensus.

Microtubule-based transport by BRIX1P1 expression — ESCA

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