BRINP3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BRINP3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRINP3-associated genes across cancer lineages are SNRPD3, SEZ6L, and PATZ1. Each is linked with BRINP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRINP3-to-partner and partner-to-BRINP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRINP3 versus SNRPD3 in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP3→partner) and Y-score (partner→BRINP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSNRPD3 →+0.467+0.453<.001.00131
GBMSEZ6L →+1.863+0.461<.001<.00131
GBMPATZ1 →+0.453+0.427.003.00631
GBMPOLR2F →+0.470+0.460<.001<.00131
GBMSOX10 →+1.580+0.459.001.00331
GBMSEPTIN3 →+1.476+0.603<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,011 associations by consensus.

BRINP3 vs SNRPD3 — GBM

Per-sample scatter of BRINP3 vs SNRPD3 in GBM (Pearson r = 0.32).

Explore this scatter interactively →

Exploration