BRINP3

Across TCGA cell cohorts, BRINP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 837 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BRINP3-associated GO terms across cancer lineages are Negative regulation of protein localization to mitochondrion, Regulation of smooth muscle cell-matrix adhesion, and Fc receptor mediated stimulatory signaling pathway. Each is linked with BRINP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BRINP3-to-partner and partner-to-BRINP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to mitochondrion grouped by BRINP3-low versus BRINP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP3→partner) and Y-score (partner→BRINP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein localization to mitochondrion →	-0.157	-1.727	<.001	.005	3	3
BONE	Regulation of smooth muscle cell-matrix adhesion →	-0.791	-1.325	.001	.006	3	3
BONE	Fc receptor mediated stimulatory signaling pathway →	-0.082	-1.165	.002	.008	3	3
BONE	Negative regulation of smooth muscle contraction →	+0.195	+1.622	.001	.005	3	3
SOFT_TISSUE	Sterol catabolic process →	+0.175	+1.346	.006	.005	3	3
SOFT_TISSUE	Response to amphetamine →	+0.156	+2.163	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 837 associations by consensus.

Negative regulation of protein localization to mitochondrion by BRINP3 expression — BONE

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