BRINP3

Across TCGA cell cohorts, BRINP3 mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible BRINP3-associated genes across cancer lineages are PRR20B, PRR20A, and PRR20D. Each is linked with BRINP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRINP3-to-partner and partner-to-BRINP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR20B grouped by BRINP3-low versus BRINP3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP3→partner) and Y-score (partner→BRINP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PRR20B →	+0.032	+4.977	<.001	.002	3	2
SOFT_TISSUE	PRR20A →	+0.032	+4.977	<.001	.002	3	2
SOFT_TISSUE	PRR20D →	+0.032	+4.977	<.001	.002	3	2
SOFT_TISSUE	PRR20E →	+0.032	+4.977	<.001	.002	3	2
LUNG_SCLC	LEUTX →	+0.034	+2.232	<.001	.007	3	2
SKIN	FAM86B1 →	+0.813	+2.523	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

PRR20B by BRINP3 expression — SOFT_TISSUE

Explore this box plot interactively →