Across TCGA patient cohorts, BRINP2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,305 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRINP2-associated genes across cancer lineages are PRODH, SEPTIN3, and RASL10A. Each is linked with BRINP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRINP2-to-partner and partner-to-BRINP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP2→partner) and Y-score (partner→BRINP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.943	+0.528	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.425	+0.659	<.001	<.001	3	1
GBM	RASL10A →	+0.620	+0.547	.007	<.001	3	1
GBM	CHGA →	+2.033	+0.697	<.001	.001	3	1
GBM	RIMS4 →	+1.019	+0.517	.001	.001	3	1
GBM	HRH3 →	+0.893	+0.675	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,305 associations by consensus.

Exploration

BRINP2 survival (RNA) · tumor vs normal (RNA) · all BRINP2 data types