Across TCGA cell cohorts, BRINP2 mutation is significantly associated with the RNA expression of many other genes, with 313 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BRINP2-associated genes across cancer lineages are OTX1, PLPPR1, and PABPC1L2B. Each is linked with BRINP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRINP2-to-partner and partner-to-BRINP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP2→partner) and Y-score (partner→BRINP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OTX1 →	+0.656	+3.451	.005	.002	3	2
LARGE_INTESTINE	PLPPR1 →	+0.367	+3.285	.001	.008	3	2
BLOOD_Myeloma	PABPC1L2B →	+0.006	+4.807	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	IL3 →	+0.012	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	PTCRA →	+0.019	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	CASP12 →	+0.028	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 313 associations by consensus.

Exploration

BRINP2 survival (RNA) · tumor vs normal (RNA) · all BRINP2 data types