BRINP1

Across TCGA cell cohorts, BRINP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,253 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible BRINP1-associated GO terms across cancer lineages are Nucleobase-containing compound transport, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Secondary alcohol biosynthetic process. Each is linked with BRINP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BRINP1-to-partner and partner-to-BRINP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleobase-containing compound transport grouped by BRINP1-low versus BRINP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRINP1→partner) and Y-score (partner→BRINP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Nucleobase-containing compound transport →	+0.040	+0.661	.002	.003	3	5
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.060	-0.759	.001	.003	3	5
SOFT_TISSUE	Secondary alcohol biosynthetic process →	+0.125	+1.229	<.001	.002	3	4
OVARY	Alternative mRNA splicing, via spliceosome →	+0.081	+0.606	.001	.008	3	4
CNS	Ventricular cardiac muscle cell differentiation →	-0.143	-0.998	<.001	<.001	3	4
SOFT_TISSUE	Cholesterol biosynthetic process →	+0.125	+1.229	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,253 associations by consensus.

Nucleobase-containing compound transport by BRINP1 expression — OVARY

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