Across TCGA patient cohorts, BRICD5 mutation is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRICD5-associated genes across cancer lineages are OR4P1P, RNU6-73P, and DUX4L19. Each is linked with BRICD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRICD5-to-partner and partner-to-BRICD5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRICD5→partner) and Y-score (partner→BRICD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4P1P →	+0.275	+6.608	<.001	.001	3	2
HNSC	RNU6-73P →	+0.560	+6.763	<.001	<.001	3	2
HNSC	DUX4L19 →	+0.041	+5.303	.006	.006	3	2
HNSC	MIR6893 →	+0.550	+5.435	<.001	.005	3	2
SKCM	SLCO1B3 →	+0.374	+4.885	<.001	<.001	3	2
HNSC	LINC01955 →	+0.060	+5.182	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

Exploration

BRICD5 survival (RNA) · tumor vs normal (RNA) · all BRICD5 data types