BRI3

Across TCGA patient cohorts, BRI3 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,343 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BRI3-associated proteins across cancer lineages are RP2, SLC17A5, and LAMTOR1. Each is linked with BRI3 in more than 6 cancer types. Because this analysis shows association rather than direction, both BRI3-to-partner and partner-to-BRI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRI3 versus RP2 in UCEC, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRI3→partner) and Y-score (partner→BRI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RP2 →	+0.462	+0.460	<.001	<.001	3	6
GBM	SLC17A5 →	+0.612	+0.493	<.001	<.001	3	6
LUAD	LAMTOR1 →	+0.265	+0.544	<.001	<.001	2	7
UCEC	LMBRD1 →	+0.549	+0.556	<.001	<.001	3	6
GBM	ALDH3B1 →	+0.584	+0.390	<.001	<.001	3	5
BRCA	REEP4_S152 →	+0.494	+0.470	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,343 associations by consensus.

BRI3 vs RP2 — UCEC

Explore this scatter interactively →