BRDTP1

Across TCGA patient cohorts, BRDTP1 mutation is significantly associated with the RNA expression of many other genes, with 3,592 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BRDTP1-associated genes across cancer lineages are RNU6-681P, RNU4-27P, and IGHD1-26. Each is linked with BRDTP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BRDTP1-to-partner and partner-to-BRDTP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-681P grouped by BRDTP1-low versus BRDTP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRDTP1→partner) and Y-score (partner→BRDTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-681P →	+0.191	+3.159	<.001	.008	3	2
SKCM	RNU4-27P →	+0.248	+3.715	<.001	<.001	3	2
UCEC	IGHD1-26 →	+0.496	+2.558	<.001	.002	3	2
UCEC	MIR1298 →	+0.057	+4.606	<.001	.001	3	2
UCEC	SNORD62A →	+0.372	+1.752	.002	.003	3	2
UCEC	LILRA6 →	+0.303	+2.168	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,592 associations by consensus.

RNU6-681P by BRDTP1 expression — SKCM

Explore this box plot interactively →