BRD9

Across TCGA cell cohorts, BRD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,930 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BRD9-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Signal transduction in response to DNA damage, and Positive regulation of DNA metabolic process. Each is linked with BRD9 in more than 15 cancer types. Because this analysis shows association rather than direction, both BRD9-to-partner and partner-to-BRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by BRD9-low versus BRD9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD9→partner) and Y-score (partner→BRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.163	+0.976	.001	.005	3	16
BONE	Signal transduction in response to DNA damage →	+0.075	+0.714	.006	<.001	3	16
BONE	Positive regulation of DNA metabolic process →	+0.092	+0.800	.002	.006	3	15
BONE	Regulation of telomere maintenance →	+0.062	+0.615	<.001	<.001	3	15
BONE	Positive regulation of chromosome organization →	+0.088	+0.750	.001	.003	3	15
BONE	DNA-templated transcription initiation →	+0.078	+0.682	<.001	.007	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,930 associations by consensus.

Protein localization to nuclear inner membrane by BRD9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →