BRD8

Across TCGA patient cohorts, BRD8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,587 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRD8-associated proteins across cancer lineages are ZMAT2, KDM3B_S314, and RBM12. Each is linked with BRD8 in more than 6 cancer types. Because this analysis shows association rather than direction, both BRD8-to-partner and partner-to-BRD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRD8 versus ZMAT2 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD8→partner) and Y-score (partner→BRD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZMAT2 →	+0.316	+0.310	<.001	<.001	3	7
UCEC	KDM3B_S314 →	+0.461	+0.570	.001	<.001	3	7
GBM	RBM12 →	+0.301	+0.414	<.001	<.001	3	6
GBM	SMC3 →	+0.323	+0.354	<.001	<.001	3	6
GBM	SREK1 →	+0.259	+0.310	<.001	<.001	3	6
GBM	BCLAF1 →	+0.374	+0.414	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,587 associations by consensus.

BRD8 vs ZMAT2 — GBM

Explore this scatter interactively →