BRD8

Across TCGA patient cohorts, BRD8 protein abundance is significantly associated with the RNA expression of many other genes, with 15,881 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BRD8-associated genes across cancer lineages are DDX51, RFC5, and USP21. Each is linked with BRD8 in more than 7 cancer types. Because this analysis shows association rather than direction, both BRD8-to-partner and partner-to-BRD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BRD8 versus DDX51 in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD8→partner) and Y-score (partner→BRD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX51 →	+0.679	+0.312	<.001	<.001	3	8
LSCC	RFC5 →	+0.777	+0.322	<.001	<.001	3	7
UCEC	USP21 →	+0.625	+0.234	<.001	<.001	3	7
UCEC	CLK2 →	+0.622	+0.231	<.001	<.001	3	7
LSCC	SART3 →	+0.471	+0.293	<.001	<.001	3	7
BRCA	TFAP4 →	+0.575	+0.183	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,881 associations by consensus.

BRD8 vs DDX51 — BRCA

Explore this scatter interactively →