Across TCGA pan-cancer cohorts, BRD7P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BRD7P3’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where BRD7P3 RNA is repressed in tumor relative to normal tissue. In most cancer types BRD7P3 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.
BRCA and LUSC are the cancer types where BRD7P3 tumor–normal differential expression is most reproducible.