BRD3

Across TCGA cell cohorts, BRD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,261 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BRD3-associated GO terms across cancer lineages are Regulation of chromatin organization, Transcription initiation-coupled chromatin remodeling, and Regulation of organelle assembly. Each is linked with BRD3 in more than 17 cancer types. Because this analysis shows association rather than direction, both BRD3-to-partner and partner-to-BRD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by BRD3-low versus BRD3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BRD3→partner) and Y-score (partner→BRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of chromatin organization →	+0.098	+0.681	<.001	<.001	3	18
STOMACH	Transcription initiation-coupled chromatin remodeling →	+0.105	+1.154	<.001	<.001	3	17
STOMACH	Regulation of organelle assembly →	+0.058	+0.862	.001	.001	3	16
STOMACH	Regulation of nucleotide-excision repair →	+0.154	+0.896	.003	.007	3	16
BONE	Nucleic acid transport →	+0.099	+0.885	<.001	<.001	3	16
BONE	RNA transport →	+0.099	+0.885	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,261 associations by consensus.

Regulation of chromatin organization by BRD3 expression — LUNG_SCLC

Explore this box plot interactively →