BPTFP1

Across TCGA pan-cancer cohorts, BPTFP1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated BPTFP1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher BPTFP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BPTFP1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

UVM, KIRC, and READ are the cancer types where BPTFP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.037	0.835	<.001	108	view →
KIRC	DFS	Tertile	IV	0.220	0.525	.001	48	view →
READ	DFS	Tertile	All	0.198	0.580	.001	48	view →
HNSC	OS	Tertile	III,IV	0.265	0.683	.007	36	view →
LIHC	OS	Tertile	All	0.226	0.773	.008	27	view →
COAD	DFS	Tertile	III,IV	0.210	0.446	.028	21	view →
STAD	DFS	Tertile	IV	0.099	0.530	.011	18	view →
SARC	OS	Tertile	All	0.507	0.756	.011	18	view →
BRCA	DFS	Tertile	III,IV	0.760	0.419	.023	12	view →
LAML	DFS	Median	All	0.531	0.241	.012	12	view →
OV	DFS	Tertile	II,III,IV	0.225	0.139	.037	12	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

BPTFP1–UVM (OS)

Open the UVM breakdown →