BPTFP1

Across TCGA pan-cancer cohorts, BPTFP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of BPTFP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BPTFP1 RNA is repressed in tumor relative to normal tissue. In most cancer types BPTFP1 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC are the cancer types where BPTFP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BPTFP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	−0.017	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

BPTFP1–HNSC

Open the HNSC breakdown →