Across TCGA cell cohorts, BPIFC RNA expression is significantly associated with the go_rna of many other GO terms, with 386 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible BPIFC-associated GO terms across cancer lineages are Negative regulation of catalytic activity, Response to amino acid, and Endosome organization. Each is linked with BPIFC in more than 3 cancer types. Because this analysis shows association rather than direction, both BPIFC-to-partner and partner-to-BPIFC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFC→partner) and Y-score (partner→BPIFC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of catalytic activity →	+0.056	+0.371	<.001	.004	3	3
LUNG_NSCLC_LUAD	Response to amino acid →	+0.041	+0.048	.001	.004	2	4
UPPER_AERODIGESTIVE_TRACT	Endosome organization →	+0.052	+0.462	.001	.005	3	3
LUNG_SCLC	Negative regulation of ruffle assembly →	+0.219	+0.755	<.001	<.001	3	3
LUNG_SCLC	Developmental maturation →	+0.036	+0.592	.002	.005	3	3
LUNG_SCLC	Regulation of microtubule depolymerization →	+0.086	+0.863	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Exploration

BPIFC survival (RNA) · tumor vs normal (RNA) · all BPIFC data types