BPIFB6

Across TCGA cell cohorts, BPIFB6 RNA expression is significantly associated with the mutation status of many other genes, with 263 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BPIFB6-associated genes across cancer lineages are MICAL2, WASHC2A, and ALMS1. Each is linked with BPIFB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFB6-to-partner and partner-to-BPIFB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MICAL2 grouped by BPIFB6-low versus BPIFB6-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB6→partner) and Y-score (partner→BPIFB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MICAL2 →	+5.000	+0.086	.006	<.001	3	2
PANCREAS	WASHC2A →	+5.000	+0.086	.006	<.001	3	2
LUNG_SCLC	ALMS1 →	+2.807	+0.008	.005	<.001	3	2
LUNG_SCLC	VAV1 →	+5.029	+0.012	.006	.001	3	2
LUNG_SCLC	RBM47 →	+5.029	+0.012	.006	.001	3	2
CNS	KIAA1549L →	+4.169	+0.029	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 263 associations by consensus.

MICAL2 by BPIFB6 expression — PANCREAS

Explore this box plot interactively →