BPIFB6

Across TCGA cell cohorts, BPIFB6 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BPIFB6-associated genes across cancer lineages are PROP1, CHRNB3, and MT1B. Each is linked with BPIFB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFB6-to-partner and partner-to-BPIFB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROP1 grouped by BPIFB6-low versus BPIFB6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB6→partner) and Y-score (partner→BPIFB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PROP1 →	+0.021	+4.376	.001	<.001	3	2
SKIN	CHRNB3 →	+0.011	+4.467	<.001	.004	3	1
SKIN	MT1B →	+0.076	+4.415	<.001	.007	3	1
SKIN	OR51A4 →	+0.010	+5.022	<.001	.002	3	1
SKIN	SMIM28 →	+0.020	+5.022	<.001	.002	3	1
LARGE_INTESTINE	BPY2 →	+0.015	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

PROP1 by BPIFB6 expression — LARGE_INTESTINE

Explore this box plot interactively →