Across TCGA cell cohorts, BPIFB3 RNA expression is significantly associated with the mutation status of many other genes, with 110 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BPIFB3-associated genes across cancer lineages are PLXNA2, PPWD1, and CHL1. Each is linked with BPIFB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFB3-to-partner and partner-to-BPIFB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB3→partner) and Y-score (partner→BPIFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	PLXNA2 →	+3.857	+0.022	.002	<.001	3	2
LUNG_NSCLC_LUAD	PPWD1 →	+3.681	+0.252	.009	.002	3	2
BLOOD_Lymphoma	CHL1 →	+3.925	+0.010	.006	<.001	3	2
PANCREAS	HOXA1 →	+4.029	+0.042	.007	<.001	3	1
PANCREAS	TRIM33 →	+5.614	+0.070	.002	<.001	3	1
PANCREAS	PCDHGA3 →	+4.029	+0.042	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

Exploration

BPIFB3 survival (RNA) · tumor vs normal (RNA) · all BPIFB3 data types