BPIFB2

Across TCGA patient cohorts, BPIFB2 mutation is significantly associated with the RNA expression of many other genes, with 822 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BPIFB2-associated genes across cancer lineages are ATP5PBP2, RN7SKP264, and RNA5SP432. Each is linked with BPIFB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BPIFB2-to-partner and partner-to-BPIFB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5PBP2 grouped by BPIFB2-low versus BPIFB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFB2→partner) and Y-score (partner→BPIFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATP5PBP2 →	+0.264	+1.855	<.001	.007	3	3
PAAD	RN7SKP264 →	+0.154	+5.213	<.001	.006	3	2
CESC	RNA5SP432 →	+0.349	+5.539	<.001	.004	3	2
SKCM	PIK3CD →	+0.715	+3.603	.007	.001	3	2
SKCM	BTBD6 →	+0.581	+2.932	<.001	<.001	3	2
SKCM	CIDECP1 →	+0.326	+2.594	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

ATP5PBP2 by BPIFB2 expression — SKCM

Explore this box plot interactively →