BPIFA3

Across TCGA patient cohorts, BPIFA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,239 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BPIFA3-associated GO terms across cancer lineages are Regulation of telomere maintenance in response to DNA damage, rRNA modification, and Hippocampus development. Each is linked with BPIFA3 in more than 9 cancer types. Because this analysis shows association rather than direction, both BPIFA3-to-partner and partner-to-BPIFA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance in response to DNA damage grouped by BPIFA3-low versus BPIFA3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA3→partner) and Y-score (partner→BPIFA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.061	+0.090	<.001	<.001	3	10
STAD	rRNA modification →	+0.069	+0.086	<.001	<.001	3	9
STAD	Hippocampus development →	+0.047	+0.077	<.001	<.001	3	9
STAD	Negative regulation of mRNA metabolic process →	+0.074	+0.084	<.001	<.001	3	9
STAD	Protein folding →	+0.079	+0.078	<.001	<.001	3	9
STAD	Spindle organization →	+0.081	+0.087	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,239 associations by consensus.

Regulation of telomere maintenance in response to DNA damage by BPIFA3 expression — STAD

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