BPIFA3

Across TCGA pan-cancer cohorts, BPIFA3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BPIFA3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where BPIFA3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BPIFA3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD and KIRC are the cancer types where BPIFA3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BPIFA3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.007	.031	1	view →
KIRC	All	IV	−0.005	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

BPIFA3–COAD

Open the COAD breakdown →