BPIFA3

Across TCGA cell cohorts, BPIFA3 RNA expression is significantly associated with the mutation status of many other genes, with 16 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BPIFA3-associated genes across cancer lineages are DYSF, TBC1D31, and BSN. Each is linked with BPIFA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFA3-to-partner and partner-to-BPIFA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYSF grouped by BPIFA3-low versus BPIFA3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA3→partner) and Y-score (partner→BPIFA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DYSF →	+4.357	+0.027	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	TBC1D31 →	+5.357	+0.036	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	BSN →	+4.357	+0.027	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZIC4 →	+5.357	+0.036	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	SP140L →	+5.357	+0.036	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF658 →	+4.357	+0.027	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

DYSF by BPIFA3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →