Across TCGA patient cohorts, BPIFA1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,186 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BPIFA1-associated genes across cancer lineages are MUC5B, BPIFB1, and PLEKHS1. Each is linked with BPIFA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BPIFA1-to-partner and partner-to-BPIFA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA1→partner) and Y-score (partner→BPIFA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MUC5B →	+2.568	+1.431	<.001	<.001	3	3
HNSC	BPIFB1 →	+2.798	+0.849	<.001	<.001	3	3
LUAD	PLEKHS1 →	+1.560	+1.556	<.001	<.001	3	3
LUAD	BPIFB2 →	+2.654	+2.070	<.001	<.001	3	3
LSCC	PDCD2L →	-0.426	-0.864	.006	.002	3	2
LUAD	BPIFA2 →	+1.867	+1.975	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,186 associations by consensus.

Exploration

BPIFA1 survival (RNA) · tumor vs normal (RNA) · all BPIFA1 data types