Across TCGA cell cohorts, BPIFA1 RNA expression is significantly associated with the mutation status of many other genes, with 654 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BPIFA1-associated genes across cancer lineages are PDLIM7, RICTOR, and CELSR1. Each is linked with BPIFA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFA1-to-partner and partner-to-BPIFA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA1→partner) and Y-score (partner→BPIFA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PDLIM7 →	+3.544	+0.241	.002	<.001	3	2
OESOPHAGUS	RICTOR →	+4.906	+0.136	.006	<.001	3	2
BLOOD_Lymphoma	CELSR1 →	+3.421	+0.305	.001	.006	3	2
LARGE_INTESTINE	NOS2 →	+2.035	+0.073	<.001	.006	3	2
LARGE_INTESTINE	CELSR3 →	+1.910	+0.073	.001	.006	3	2
LARGE_INTESTINE	DIS3 →	+2.688	+0.152	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 654 associations by consensus.

Exploration

BPIFA1 survival (RNA) · tumor vs normal (RNA) · all BPIFA1 data types