Across TCGA cell cohorts, BPIFA1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BPIFA1-associated genes across cancer lineages are MAGEB4, PRORY, and C16orf90. Each is linked with BPIFA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BPIFA1-to-partner and partner-to-BPIFA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPIFA1→partner) and Y-score (partner→BPIFA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAGEB4 →	+0.010	+5.022	<.001	.002	3	1
SKIN	PRORY →	+0.984	+4.273	<.001	.006	3	1
SKIN	C16orf90 →	+0.025	+4.467	.001	.004	3	1
LARGE_INTESTINE	CENPVL1 →	+0.190	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR4A47 →	+0.022	+5.022	<.001	.002	3	1
LUNG_NSCLC_LUAD	OOSP4B →	+0.017	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

BPIFA1 survival (RNA) · tumor vs normal (RNA) · all BPIFA1 data types