BPGM

Across TCGA patient cohorts, BPGM protein abundance is significantly associated with the RNA expression of many other genes, with 6,326 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BPGM-associated genes across cancer lineages are HBA2, HBA1, and HBB. Each is linked with BPGM in more than 6 cancer types. Because this analysis shows association rather than direction, both BPGM-to-partner and partner-to-BPGM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BPGM versus HBA2 in OV, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BPGM→partner) and Y-score (partner→BPGM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HBA2 →	+2.188	+0.782	<.001	<.001	3	7
GBM	HBA1 →	+1.724	+0.654	<.001	<.001	3	7
OV	HBB →	+2.210	+0.702	<.001	<.001	3	7
PDAC	PPBP →	+1.097	+0.497	.001	<.001	3	6
CCRCC	HEMGN →	+0.588	+0.712	<.001	<.001	3	6
OV	DUSP1 →	+1.341	+0.448	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,326 associations by consensus.

BPGM vs HBA2 — OV

Explore this scatter interactively →