BORCS8-MEF2B

Across TCGA patient cohorts, BORCS8-MEF2B protein abundance is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BORCS8-MEF2B-associated genes across cancer lineages are IL2, NCF2, and ZNF670-ZNF695. Each is linked with BORCS8-MEF2B in more than 1 cancer types. Because this analysis shows association rather than direction, both BORCS8-MEF2B-to-partner and partner-to-BORCS8-MEF2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BORCS8-MEF2B versus IL2 in BRCA, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS8-MEF2B→partner) and Y-score (partner→BORCS8-MEF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL2 →	+0.349	+1.218	.004	.001	3	1
BRCA	NCF2 →	+0.520	+1.218	.003	.001	3	1
BRCA	ZNF670-ZNF695 →	+0.411	+1.218	.002	.001	3	1
BRCA	BAAT →	+0.158	+1.218	.001	.001	3	1
BRCA	TTBK1 →	+0.341	+1.218	<.001	.001	3	1
BRCA	STC1 →	+2.465	+1.218	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

BORCS8-MEF2B vs IL2 — BRCA

Explore this scatter interactively →