BORCS8-MEF2B

Across TCGA patient cohorts, BORCS8-MEF2B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BORCS8-MEF2B-associated genes across cancer lineages are MIR4752, MIR4476, and MIR412. Each is linked with BORCS8-MEF2B in more than 1 cancer types. Because this analysis shows association rather than direction, both BORCS8-MEF2B-to-partner and partner-to-BORCS8-MEF2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4752 grouped by BORCS8-MEF2B-low versus BORCS8-MEF2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS8-MEF2B→partner) and Y-score (partner→BORCS8-MEF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4752 →	+0.502	+8.066	<.001	.007	3	1
UCEC	MIR4476 →	+0.736	+8.066	<.001	.007	3	1
UCEC	MIR412 →	+0.621	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MIR4752 by BORCS8-MEF2B expression — UCEC

Explore this box plot interactively →