BORCS7

Across TCGA patient cohorts, BORCS7 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BORCS7-associated genes across cancer lineages are MIR6879, EDDM3DP, and RNU6-206P. Each is linked with BORCS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both BORCS7-to-partner and partner-to-BORCS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6879 grouped by BORCS7-low versus BORCS7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BORCS7→partner) and Y-score (partner→BORCS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6879 →	+0.530	+8.055	<.001	.007	3	1
COAD	EDDM3DP →	+0.503	+5.435	<.001	.005	3	1
UCEC	RNU6-206P →	+0.757	+7.245	<.001	<.001	3	1
UCEC	IGHD1-26 →	+1.890	+5.484	<.001	.005	3	1
UCEC	IGHD6-6 →	+1.667	+5.420	<.001	.005	3	1
UCEC	RN7SL191P →	+0.301	+5.081	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MIR6879 by BORCS7 expression — BRCA

Explore this box plot interactively →