BORCS7-ASMT

Across TCGA pan-cancer cohorts, BORCS7-ASMT RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated BORCS7-ASMT data layer.

The strongest signal is observed in mesothelioma (MESO), where higher BORCS7-ASMT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BORCS7-ASMT expression acts as an unfavorable survival marker.

MESO, ESCA, and UVM are the cancer types where BORCS7-ASMT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.102	0.552	<.001	135	view →
ESCA	OS	Tertile	II,III,IV	0.505	0.723	.007	45	view →
UVM	DFS	Tertile	All	0.189	0.763	.004	18	view →
SARC	OS	Tertile	All	0.182	0.630	<.001	18	view →
SKCM	DFS	Tertile	All	0.420	0.646	.044	9	view →
BLCA	DFS	Tertile	III,IV	0.163	0.493	.036	9	view →
THYM	DFS	Tertile	II,III,IV	0.123	0.760	.007	9	view →
READ	DFS	Tertile	II,III,IV	0.162	0.707	.031	9	view →
LUSC	DFS	Tertile	II,III,IV	0.135	0.663	.015	9	view →
KIRP	OS	Tertile	All	0.447	0.724	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

BORCS7-ASMT–MESO (OS)

Open the MESO breakdown →