BORCS7-ASMT

Across TCGA pan-cancer cohorts, BORCS7-ASMT RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of BORCS7-ASMT’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where BORCS7-ASMT RNA is repressed in tumor relative to normal tissue. In most cancer types BORCS7-ASMT is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

PAAD are the cancer types where BORCS7-ASMT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BORCS7-ASMT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Male	All	−0.035	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

BORCS7-ASMT–PAAD

Open the PAAD breakdown →