BOLL

Across TCGA patient cohorts, BOLL RNA expression is significantly associated with the go_rna of many other GO terms, with 6,920 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BOLL-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Positive regulation of protein modification by small protein conjugation or removal, and Positive regulation of chromosome organization. Each is linked with BOLL in more than 25 cancer types. Because this analysis shows association rather than direction, both BOLL-to-partner and partner-to-BOLL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of post-translational protein modification grouped by BOLL-low versus BOLL-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLL→partner) and Y-score (partner→BOLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of post-translational protein modification →	+0.071	+0.222	<.001	<.001	3	26
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.070	+0.236	<.001	<.001	3	25
ESCA	Positive regulation of chromosome organization →	+0.082	+0.659	<.001	<.001	3	24
STAD	RNA modification →	+0.065	+0.276	<.001	<.001	3	24
STAD	Endosomal transport →	+0.068	+0.250	<.001	<.001	3	24
ESCA	Regulation of protein ubiquitination →	+0.080	+0.750	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,920 associations by consensus.

Positive regulation of post-translational protein modification by BOLL expression — STAD

Explore this box plot interactively →