BOLL

Across TCGA cell cohorts, BOLL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,022 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BOLL-associated GO terms across cancer lineages are Regulation of mRNA processing, Nucleic acid catabolic process, and Promoter clearance during DNA-templated transcription. Each is linked with BOLL in more than 11 cancer types. Because this analysis shows association rather than direction, both BOLL-to-partner and partner-to-BOLL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by BOLL-low versus BOLL-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLL→partner) and Y-score (partner→BOLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of mRNA processing →	+0.106	+0.044	<.001	.007	3	12
STOMACH	Nucleic acid catabolic process →	+0.052	+0.082	<.001	.006	3	12
BONE	Promoter clearance during DNA-templated transcription →	+0.100	+0.032	<.001	.007	3	11
BONE	RNA polymerase II promoter clearance →	+0.100	+0.032	<.001	.007	3	11
BONE	Regulation of mRNA splicing, via spliceosome →	+0.109	+0.057	<.001	.005	3	11
BONE	mRNA transport →	+0.132	+0.055	<.001	.009	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,022 associations by consensus.

Regulation of mRNA processing by BOLL expression — BONE

Explore this box plot interactively →