BOLA3

Across TCGA cell cohorts, BOLA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,396 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BOLA3-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, Meiotic chromosome segregation, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with BOLA3 in more than 14 cancer types. Because this analysis shows association rather than direction, both BOLA3-to-partner and partner-to-BOLA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [2Fe-2S] cluster assembly grouped by BOLA3-low versus BOLA3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA3→partner) and Y-score (partner→BOLA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	[2Fe-2S] cluster assembly →	+0.151	+0.710	<.001	<.001	3	15
STOMACH	Meiotic chromosome segregation →	+0.133	+1.078	.004	.007	3	13
OVARY	Negative regulation of hematopoietic stem cell differentiation →	-0.153	-0.684	<.001	<.001	3	11
LUNG_SCLC	Sperm motility →	+0.102	+0.753	.001	<.001	3	11
BLOOD_Myeloma	Iron-sulfur cluster assembly →	+0.103	+0.987	.001	<.001	3	11
BLOOD_Myeloma	Metallo-sulfur cluster assembly →	+0.103	+0.987	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,396 associations by consensus.

[2Fe-2S] cluster assembly by BOLA3 expression — LUNG_SCLC

Explore this box plot interactively →