BOLA2-SMG1P6

Across TCGA pan-cancer cohorts, BOLA2-SMG1P6 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated BOLA2-SMG1P6 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BOLA2-SMG1P6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BOLA2-SMG1P6 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

ACC, KIRP, and BLCA are the cancer types where BOLA2-SMG1P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.404	0.752	<.001	83	view →
KIRP	DFS	Median	IV	0.036	0.528	.001	45	view →
BLCA	DFS	Median	All	0.360	0.608	.001	43	view →
UVM	DFS	Median	III,IV	0.363	0.699	.005	40	view →
LIHC	OS	Tertile	All	0.592	0.761	.001	39	view →
SARC	DFS	Median	All	0.409	0.621	<.001	38	view →
MESO	OS	Median	All	0.429	0.647	.001	32	view →
COAD	DFS	Quartile	All	0.698	0.873	.005	32	view →
KIRC	OS	Quartile	All	0.699	0.538	.010	30	view →
ESCA	OS	Tertile	III,IV	0.326	0.688	<.001	25	view →
BRCA	OS	Tertile	II,III,IV	0.415	0.678	.001	20	view →
SKCM	DFS	Tertile	IV	0.657	0.153	.006	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

BOLA2-SMG1P6–ACC (DFS)

Open the ACC breakdown →