BOK

Across TCGA patient cohorts, BOK protein abundance is significantly associated with the RNA expression of many other genes, with 14,209 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BOK-associated genes across cancer lineages are ASF1B, ASPA, and PDE1A. Each is linked with BOK in more than 4 cancer types. Because this analysis shows association rather than direction, both BOK-to-partner and partner-to-BOK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BOK versus ASF1B in UCEC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOK→partner) and Y-score (partner→BOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASF1B →	-0.884	-0.436	<.001	<.001	3	5
LUAD	ASPA →	+0.607	+0.448	<.001	<.001	3	5
CCRCC	PDE1A →	+0.936	+0.375	<.001	.001	3	5
UCEC	NCAPH →	-0.668	-0.424	<.001	<.001	3	5
UCEC	ADGRB3 →	+0.606	+0.388	.003	<.001	3	5
UCEC	LRRC4C →	+0.974	+0.450	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,209 associations by consensus.

BOK vs ASF1B — UCEC

Explore this scatter interactively →