BOK-AS1

Across TCGA pan-cancer cohorts, BOK-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BOK-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BOK-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BOK-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

ACC, COAD, and ESCA are the cancer types where BOK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.333	0.664	<.001	126	view →
COAD	OS	Quartile	II,III,IV	0.616	0.831	.006	53	view →
ESCA	OS	Tertile	All	0.679	0.409	.001	53	view →
KIRP	OS	Tertile	III,IV	0.442	0.836	.004	50	view →
LUAD	OS	Median	All	0.855	0.771	.002	38	view →
MESO	DFS	Median	IV	0.189	0.521	.002	30	view →
SKCM	DFS	Tertile	IV	0.016	0.541	.008	15	view →
STAD	DFS	Tertile	IV	0.096	0.458	.002	12	view →
LAML	DFS	Tertile	All	0.721	0.487	.027	12	view →
KIRC	DFS	Tertile	II,III,IV	0.609	0.779	.017	12	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	11	view →
SARC	OS	Quartile	All	0.935	0.802	.003	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BOK-AS1–ACC (DFS)

Open the ACC breakdown →