BNIPL

Across TCGA patient cohorts, BNIPL protein abundance is significantly associated with the RNA expression of many other genes, with 6,311 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BNIPL-associated genes across cancer lineages are ARHGEF35, USH1G, and ZNF185. Each is linked with BNIPL in more than 2 cancer types. Because this analysis shows association rather than direction, both BNIPL-to-partner and partner-to-BNIPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BNIPL versus ARHGEF35 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIPL→partner) and Y-score (partner→BNIPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARHGEF35 →	+0.981	+1.031	.006	<.001	3	3
LSCC	USH1G →	+1.167	+0.689	<.001	.003	3	3
LSCC	ZNF185 →	+1.081	+0.847	<.001	<.001	3	3
LSCC	BAIAP2 →	+0.848	+0.654	<.001	<.001	3	3
UCEC	SIX1 →	-3.321	-1.148	<.001	.008	3	2
UCEC	RRAGD →	-1.158	-0.774	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,311 associations by consensus.

BNIPL vs ARHGEF35 — UCEC

Explore this scatter interactively →