BNIP3P8

Across TCGA pan-cancer cohorts, BNIP3P8 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated BNIP3P8 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BNIP3P8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P8 expression acts as an unfavorable survival marker, although some lineages such as STAD and BLCA show a favorable association.

KIRC, THCA, and ACC are the cancer types where BNIP3P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.525	0.695	<.001	110	view →
THCA	OS	Tertile	III,IV	0.736	0.950	.003	48	view →
ACC	DFS	Tertile	All	0.155	0.648	<.001	48	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	36	view →
CHOL	DFS	Tertile	All	0.143	0.584	.004	36	view →
LUSC	OS	Tertile	III,IV	0.560	0.712	.016	30	view →
STAD	OS	Tertile	IV	0.756	0.223	.013	19	view →
UVM	OS	Tertile	All	0.283	0.707	.013	18	view →
BLCA	OS	Median	III,IV	0.718	0.614	.025	7	view →
SARC	OS	Tertile	All	0.197	0.609	.012	6	view →
PCPG	OS	Tertile	All	0.915	0.991	.011	6	view →
LAML	DFS	Quartile	All	0.490	0.291	.041	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

BNIP3P8–KIRC (OS)

Open the KIRC breakdown →