BNIP3P8

Across TCGA pan-cancer cohorts, BNIP3P8 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of BNIP3P8’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where BNIP3P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BNIP3P8 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

LUSC, UCEC, and BRCA are the cancer types where BNIP3P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.052	.018	4	view →
UCEC	All	All	+0.168	.043	2	view →
BRCA	All	All	+0.148	.037	2	view →
KIRP	All	II,III,IV	−0.090	.027	2	view →
STAD	Male	II,III,IV	+0.124	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

BNIP3P8–LUSC

Open the LUSC breakdown →