BNIP3P6

Across TCGA pan-cancer cohorts, BNIP3P6 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated BNIP3P6 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher BNIP3P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P6 expression acts as an unfavorable survival marker, although some lineages such as DLBC show a favorable association.

READ, KIRC, and LUAD are the cancer types where BNIP3P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.482	0.832	<.001	126	view →
KIRC	OS	Tertile	All	0.474	0.885	<.001	120	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	81	view →
LAML	DFS	Tertile	All	0.081	0.572	.003	36	view →
STAD	DFS	Tertile	III,IV	0.363	0.625	.003	36	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
COAD	DFS	Tertile	IV	0.117	0.493	.002	27	view →
LGG	OS	Tertile	All	0.388	0.811	.028	18	view →
LUSC	DFS	Tertile	II,III,IV	0.386	0.714	.001	18	view →
DLBC	DFS	Median	II,III,IV	0.906	0.618	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

BNIP3P6–READ (OS)

Open the READ breakdown →