BNIP3P37

Across TCGA pan-cancer cohorts, BNIP3P37 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BNIP3P37 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BNIP3P37 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P37 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

KIRC, SKCM, and LGG are the cancer types where BNIP3P37 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	II,III,IV	0.546	0.733	<.001	97	view →
SKCM	OS	Tertile	All	0.214	0.364	<.001	60	view →
LGG	OS	Median	All	0.855	0.931	<.001	31	view →
READ	DFS	Tertile	II,III,IV	0.829	0.333	.007	27	view →
ESCA	DFS	Quartile	III,IV	0.659	0.296	.003	24	view →
OV	OS	Median	IV	0.502	0.270	.002	14	view →
LUAD	DFS	Tertile	IV	0.307	0.632	.045	12	view →
THYM	OS	Median	All	1.000	0.921	.011	11	view →
LUSC	DFS	Tertile	II,III,IV	0.600	0.758	.009	7	view →
CHOL	DFS	Tertile	III,IV	0.133	0.779	.038	6	view →
UCS	DFS	Median	IV	0.811	0.514	.039	6	view →
DLBC	DFS	Tertile	II,III,IV	1.000	0.220	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BNIP3P37–KIRC (OS)

Open the KIRC breakdown →